Background:This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Disrupted meiotic cDNA 1 homolog ,Disrupted meiotic cDNA 1, yeast, homolog of,dJ199H16.1,DMC 1,DMC1,DMC1 dosage suppressor of mck1 homolog,DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast),DMC1 homologue ,DMC1,DMC1H,DNA meiotic recombinase 1,HsLim15,LIM15,Meiotic recombination protein DMC1/LIM15 homolog,MGC150472,MGC150473
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DMC1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):11144
Swissprot:Q14565
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling