Background：This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp （DEAD）, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms：DEAD （Asp-Glu-Ala-Asp） box polypeptide 46,DEAD box protein 46,Probable ATP dependent RNA helicase DDX46,PRP5 homolog,Prp5 like DEAD-box protein ,PRPF5,RNA helicase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DDX46
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：1000
Gene_ID（human）：9879
Swissprot：Q7L014
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
