Background：This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia （PMID：18378094）. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms：hLON,hLON ATP dependent protease,LON,lon peptidase 1,mitochondrial,LON protease,Lon protease homolog,Lon protease like protein,Lon protease-like protein,LONHs,LONM,LONP,Lonp1,MGC1498,mitochondrial,Mitochondrial ATP dependent protease Lon,Mitochondrial ATP-dependent protease Lon,Mitochondrial lon peptidase 1,PIM1,Protease serine 15,PRSS15,Serine protease 15
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human LONP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：9361
Swissprot：P36776
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism
