Background：Staufen is a member of the family of double-stranded RNA （dsRNA）-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum （RER）, implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
仕様
Synonyms：Double stranded RNA binding protein Staufen homolog 1,Double stranded RNA binding protein Staufen homolog,Double-stranded RNA-binding protein Staufen homolog 1,FLJ25010,MGC124588,PPP1R150,STAU ,STAU1,STAU1,staufen,Staufen RNA binding protein （Drosophila）,Staufen RNA binding protein homolog 1,Staufen, Drosophila, homolog of, 1,Staufen, RNA binding protein, homolog 1 （Drosophila）,staufen-like
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human STAU1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：6780
Swissprot：O95793
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
