Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
仕様
Synonyms:2A9,5B10,CABP,CACY,Calcyclin,Growth factor inducible protein 2A9,Growth factor-inducible protein 2A9,MLN 4,MLN4,OTTHUMP00000015472,OTTHUMP00000015473,PRA,PRAGrowth factor inducible protein 2A9,Prolactin receptor associated protein,Prolactin receptor-associated protein,Protein S100 A6,Protein S100-A6,S100 A6,S100 calcium binding protein A6 (calcyclin),S100 calcium binding protein A6,S100 calcium-binding protein A6,S100A6,S10A6
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human S100A6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000
Gene_ID(human):6277
Swissprot:P06703
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling