Background:The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
仕様
Synonyms:A1 38 kDa subunit,Activator 1 38 kDa subunit,Activator 1 subunit 3,HGNC:9971,MGC5276,Replication factor C (activator 1) 3,Replication factor C (activator 1) 3,38kDa,Replication factor C 3,Replication factor C 38 kDa subunit,Replication factor C subunit 3,RF-C 38 kDa subunit,RFC 38 kD subunit,RFC 38 kDa subunit,RFC3,RFC3,RFC38
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RFC3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):5983
Swissprot:P40938
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling