Background:This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
仕様
Synonyms:1190001O17Rik,1700010A06Rik,c myc binding protein,c-myc binding protein MM 1,C-myc-binding protein Mm-1,D15Ertd697e,EIG 1,Eig1,MGC5329,MGC71907,MM 1,MM1,Myc modulator 1,PFD5,PFD5,PFDN5,Prefoldin 5,Prefoldin subunit 5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PFDN5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000
Gene_ID(human):5204
Swissprot:Q99471
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction