Background：The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：51 kDa FK506 binding protein 5,51 kDa FK506 binding protein,51 kDa FK506-binding protein,51 kDa FKBP,54 kDa progesterone receptor associated immunophilin,54 kDa progesterone receptor-associated immunophilin,AIG 6,AIG6,Androgen regulated protein 6,Androgen-regulated protein 6,FF1 antigen,FK506 binding protein 5,FK506-binding protein 5,FKBP 5,FKBP 51,FKBP 54,FKBP-5,FKBP-51,FKBP5,FKBP5,FKBP54,HSP90 binding immunophilin,HSP90-binding immunophilin,MGC111006,OTTHUMP00000016268,P54,Peptidyl prolyl cis trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP5,Peptidylprolyl cis trans isomerase,PPIase,PPIase FKBP5,Ptg 10,Ptg10,Rotamase,T cell FK506 binding protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human FKBP5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：200 - 1：2000
Gene_ID（human）：2289
Swissprot：Q13451
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
