Background:The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
仕様
Synonyms:Coprogen oxidase,COPROPORPHYRIA,Coproporphyrinogen III oxidase,Coproporphyrinogen-III oxidase,Coproporphyrinogenase,COX,CPO,Cpox,CPX,HEM 6,Hem-6,Hem6,HEM6,mitochondrial
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human CPOX
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):1371
Swissprot:P36551
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction