Background：Cytochrome c oxidase （COX）, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 （liver isoform） of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 （heart/muscle isoform） of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66％ amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene （COX6A1P） on chromosome 1p31.1 has been documented.
仕様
Synonyms：COX VIa L,COX VIa-L,COX6A,COX6A1,COX6AL,CX6A1,Cytochrome c oxidase polypeptide VIa liver,Cytochrome c oxidase polypeptide VIa-liver,Cytochrome c oxidase subunit 6A1,Cytochrome c oxidase subunit 6A1 mitochondrial,Cytochrome C oxidase subunit VIa homolog,Cytochrome c oxidase subunit VIA liver,Cytochrome c oxidase subunit VIa polypeptide 1,Cytochrome c oxidase subunit VIA-liver,MGC104500,mitochondrial
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human COX6A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
