Background:This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:C75963,Chloride channel Ka,Chloride channel kidney A,Chloride channel protein ClC Ka,Chloride channel protein ClC-Ka,ClC K1,ClC-K1,CLCK1,hClC Ka,MGC61490,MGC93313,RP23-308N2.5
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human CLCNKA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000
Gene_ID(human):1187
Swissprot:P51800
Isotype:IgG
Research Areas:Metabolism, Neuroscience, Signal transduction