Background:This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.
仕様
Synonyms:AHDS,DXS 128,DXS 128E,DXS128,DXS128 E,DXS128E,MCT 7,MCT 8,MCT7,MCT8,Monocarboxylate transporter 7,Monocarboxylate transporter 8,MOT 8,MOT8,MRX 22,MRX22,SLC16 A2 ,SLC16A 2,SLC16A2,Solute carrier family 16 (monocarboxylic acid transporters), member 2,Solute carrier family 16 member 2,Solute carrier family 16, member 2 (monocarboxylic acid transporter 8) ,Solute carrier family 16, member 2 (thyroid hormone transporter),Solute carrier family 16, member 2,X linked PEST containing transporter,X-linked PEST-containing transporter,XPCT
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human SLC16A2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.