Background:Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:END1,HGNC:14583,hVPS11,PEP5,PP3476,RING finger protein 108,RNF108,Vacuolar protein sorting 11 (yeast homolog),Vacuolar protein sorting 11 (yeast),Vacuolar protein sorting 11 homolog (S. cerevisiae),Vacuolar protein sorting 11 homolog,Vacuolar protein sorting associated protein 11 homolog,Vacuolar protein sorting protein 11,Vacuolar protein sorting-associated protein 11 homolog,vps11,VPS11
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human VPS11
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.