Background：The Fanconi anemia complementation group （FANC） currently includes FANCA, FANCB, FANCC, FANCD1 （also called BRCA2）, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ （also called BRIP1）, FANCL, FANCM and FANCN （also called PALB2）. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
仕様
Synonyms：FANCI,FANCI gene,FANCI,Fanconi anemia group I protein,Fanconi anemia, complementation group I,FLJ10719,FLJ14658,KIAA1794,Protein FACI,Protein FANCI
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human FANCI
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：55215
Swissprot：Q9NVI1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
