Background:This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms:5 methycytoisine methyltransferase,D13Wsu123e,FLJ20303,hTrm4,MISU,Myc induced SUN domain containing protein,NOL1/NOP2/Sun domain family 2,NOL1/NOP2/Sun domain family 2 protein,NOL1/NOP2/Sun domain family member 2,NSUN 2,NSUN2,NSUN2,SAKI,Substrate of AIM1/Aurora kinase B,TRM4,tRNA (cytosine 5 ) methyltransferase,tRNA (cytosine 5 ) methyltransferase NSUN2,tRNA (cytosine(34)-C(5))-methyltransferase,tRNA (cytosine-5-)-methyltransferase,tRNA methyltransferase 4 homolo,tRNA methyltransferase 4 homolog
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human NSUN2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.