Background:Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
仕様
Synonyms:ccnb2,CCNB2,CycB2,Cyclin B2,G2 mitotic specific cyclin B2,G2/mitotic specific cyclin B2,G2/mitotic-specific cyclin-B2,HsT17299,MGC108931,MGC140694
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human CCNB2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):9133
Swissprot:O95067
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling