Background：This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：H3 K9 HMTase1,H3-K9-HMTase 1,Histone H3-K9 methyltransferase 1,Histone H3-K9 methyltransferase1,Histone lysine N methyltransferase, H3 lysine 9 specific 1,Histone-lysine N-methyltransferase SUV39H1,KMT1 A,KMT1A,Lysine N methyltransferase 1A,Lysine N-methyltransferase 1A,MG44,mIS6,Position-effect variegation 3-9 homolog,Su（var）3 9 homolog 1,Su（var）3-9 homolog 1,Suppressor of variegation 3 9 homolog 1 （Drosophila）,Suppressor of variegation 3-9 homolog 1,SUV39 H1,SUV39H,SUV39H1,SUV91
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human SUV39H1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：6839
Swissprot：O43463
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Microbiology
