Background:This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:glutamic acid- and leucine-rich protein 1,HMX3,MNAR,Modulator of non-genomic activity of estrogen receptor,Modulator of nongenomic activity of estrogen receptor,P160,Pelp1,PELP1 proline glutamic acid leucine rich protein 1,PELP1,proline and glutamic acid rich nuclear protein,Proline glutamate and leucine rich protein 1,Proline-,proline-, glutamic acid- and leucine-rich protein 1,Transcription factor HMX3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PELP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):27043
Swissprot:Q8IZL8
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction