Background：This gene is a member of the nuclear factor of activated T cells （NFAT） family. The product of this gene is a DNA-binding protein with a REL-homology region （RHR） and an NFAT-homology region （NHR）. This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor （TCR） stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
仕様
Synonyms：AI607462,cytoplasmic 2,KIAA0611,NF ATc2,NF ATp,NF-ATc2,NF-ATp,NFAC2,NFAT 1,NFAT pre existing subunit,NFAT pre-existing subunit,NFAT transcription complex,preexisting component,NFAT1,NFAT1-D,NFATc2,NFATp,Nuclear factor of activated T cells cytoplasmic 2,Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2,Nuclear factor of activated T cells pre-existing component,Nuclear factor of activated T cells,preexisting component,Nuclear factor of activated T-cells,Preexisting nuclear factor of activated T cells 2,T cell transcription factor NFAT 1,T-cell transcription factor NFAT1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human NFATC2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：1000
Gene_ID（human）：4773
Swissprot：Q13469
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal transduction
