Background：This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
仕様
Synonyms：E3 ubiquitin-protein ligase TRIM63,FLJ32380,IRF,Iris RING finger protein,MURF 1,MURF-1,MuRF1,MURF2,Muscle specific ring finger protein 1,Muscle specific ring finger protein 2,Muscle-specific RING finger protein 1,OTTHUMP00000008701,RING finger protein 28,RNF 28,RNF28,SMRZ,Striated muscle RING zinc finger protein,TRI63,TRIM 63,Trim63,Tripartite motif containing 63,tripartite motif containing 63,E3 ubiquitin protein ligase,Tripartite motif containing protein 63,Tripartite motif-containing protein 63,Ubiquitin ligase TRIM63
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：A synthetic peptide of human TRIM63
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：84676
Swissprot：Q969Q1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling
