Background:The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
仕様
Synonyms:DNA repair protein RAD52,DNA repair protein RAD52,DNA repair protein RAD52 homolog,RAD 52,Rad52,RAD52 homolog (S. cerevisiae),RAD52 homolog (S. cerevisiae),RAD52 homolog,RAD52,Recombination protein RAD52,Recombination protein RAD52,Rhabdomyosarcoma antigen MU RMS 40.23
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RAD52
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:1000
Gene_ID(human):5893
Swissprot:P43351
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling