Background：This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 （PDZ） domain and a semi-Cdc42/Rac interactive binding （CRIB） domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition （EMT） that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：0710008C04Rik,2610010A15Rik,Par 6 partitioning defective 6 C elegans homolog alpha,Par 6 partitioning defective 6 homolog alpha,Par 6 partitioning defective 6 homolog alpha C elegans,PAR 6A,PAR-6 alpha,PAR-6,par-6 family cell polarity regulator alpha,PAR-6A,PAR6,PAR6A,PAR6alpha,PAR6C,Pard6a,Partitioning defective 6 homolog alpha,partitioning-defective protein 6,partitioning-defective protein 6, C. elegans,homolog of,alpha,Tax interacting protein 40,Tax interaction protein 40,TAX40,TIP 40,TIP-40,TIP40
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human PARD6A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：50855
Swissprot：Q9NPB6
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
