Background:The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
仕様
Synonyms:2310001G03Rik,PAR 4,PAR-4,Pawr,PAWR,PRKC Apoptosis WT1 Regulator,PRKC apoptosis WT1 regulator protein,Prostate apoptosis response 4 protein,Prostate apoptosis response protein 4,prostate apoptosis response protein PAR-4,Transcriptional repressor Par-4-like protein PAWR,Transcriptional repressor PAR4,WT1 Interacting Protein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human PAWR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:100
Gene_ID(human):5074
Swissprot:Q96IZ0
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism