Background:This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
仕様
Synonyms:14 3 3 gamma,14 3 3 protein gamma,14 3 3 protein gamma subtype,14 3 3gamma,14-3-3 protein gamma,1433G,3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide,KCIP 1,KCIP-1,KCIP1,N-terminally processed,Protein kinase C inhibitor protein 1,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide,Ywhag
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human YWHAG
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):7532
Swissprot:P61981
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells