Background：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
仕様
Synonyms：ABC 29,ABC29,ABCC 1,ABCC,Abcc1,ATP binding cassette sub family C （CFTR/MRP） member 1,ATP binding cassette sub-family C member 1,ATP binding cassette subfamily C member 1,ATP binding cassette transporter variant ABCC1delta ex13,ATP binding cassette transporter variant ABCC1delta ex13＆14,ATP binding cassette transporter variant ABCC1delta ex25,ATP binding cassette transporter variant ABCC1delta ex25＆26,ATP binding cassette,sub-family C （CFTR/MRP）,member 1,ATP-binding cassette sub-family C member 1,DKFZp686N04233,DKFZp781G125,GS X,GSX,Leukotriene C（4） transporter,LTC4 transporter,MRP 1,MRP,MRP1,MRP1,Multidrug resistance associated protein 1,Multidrug resistance protein,Multidrug resistance-associated protein 1,Multiple drug resistance associated protein,Multiple drug resistance protein 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human ABCC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：1000 IHC1：50 - 1：200
Gene_ID（human）：4363
Swissprot：P33527
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
