Background:The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
仕様
Synonyms:CDC 37,Cdc37,CDC37 cell division cycle 37 homolog,CDC37 cell division cycle 37 S cerevisiae homolog,CDC37 cell division cycle 37,S cerevisiae,homolog of,Cdc37 homolog,CDC37 protein,CDC37,CDC37A,cell division cycle 37,Cell division cycle 37 homolog,Hsp90 chaperone protein kinase targeting subunit,Hsp90 chaperone protein kinase targeting subunit p50Cdc37,Hsp90 chaperone protein kinase-targeting subunit,Hsp90 co chaperone Cdc37,Hsp90 co-chaperone Cdc37,p50,p50Cdc37,S cerevisiae hypothetical protein CDC37
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human CDC37
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:1000
Gene_ID(human):11140
Swissprot:Q16543
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling