Background：This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
仕様
Synonyms：Age related hearing loss 1,Ahl 1,Ahl,Ahl1,Bob,Bobby,Bus,Bustling,Cadherin 23,Cadherin23,CDH 23,Mdfw,Modifier of deaf waddler,nmf112,nmf181,nmf252,Otocadherin,USH 1D,USH1 D,USH1D,Waltzer
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human CDH23
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
