Background:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
仕様
Synonyms:ACO,ACO protease,EC 3.4.21.,HSRNASPH,Kallikrein 15 isoform CRA_d,Kallikrein like serine protease,Kallikrein related peptidase 15,Kallikrein-15,Kallikrein15,KLK 15,KLK15,KLK15 protein,KLK15,MGC129160,MGC129345,NSRNASPH,Prostin,Prostinogen
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human KLK15
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):55554
Swissprot:Q9H2R5
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction