Background：This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
仕様
Synonyms：Adipocyte differentiation inhibitor protein,Brevideltin,Delta like 1 homolog,Delta like homolog,Delta like protein,Delta1,DLK 1,DLK,DLK-1,DLK1,DLK1,FA 1,FA1,Fetal antigen 1,pG2,Preadipocyte factor 1,Pref 1,Pref,Pref1,Protein delta homolog 1,Secredeltin,ZOG
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DLK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：200 - 1：500
Gene_ID（human）：8788
Swissprot：P80370
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells
