Background：This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
仕様
Synonyms： ATP binding cassette sub family B member 8,ABCB8,ABCB8,ATP binding cassette sub family B （MDR/TAP） member 8,ATP binding cassette sub family B member 8 mitochondrial,ATP-binding cassette sub-family B member 8,EST328128,M ABC1,M-ABC1,MABC1,Mitochondrial ABC protein,mitochondrial,Mitochondrial ATP binding cassette 1,Mitochondrial ATP-binding cassette 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ABCB8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：11194
Swissprot：Q9NUT2
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
