Background：The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
仕様
Synonyms：5530600P05Rik,Adenomatous polyposis coli binding protein EB 1,Adenomatous polyposis coli binding protein EB1,AI462499,AI504412,APC binding protein EB 1,APC binding protein EB1 ,APC-binding protein EB1,AW260097,BIM1p,D2Ertd459e,EB 1,EB1,End binding protein 1 ,End-binding protein 1,fa01e12,fc23e11,fi33c06,MAPRE 1,MAPRE1,Mapre3,MARE1,MGC117374,MGC129946,MGC52508 ,Microtubule associated protein RP/EB family member 1,Microtubule-associated protein RP/EB family member 1,wu：fa01e12,wu：fc23e11,wu：fi33c06,zgc：55428,zgc：77807,zgc：85755
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MAPRE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：22919
Swissprot：Q15691
Isotype：IgG
Research Areas：Cancer, Signal transduction, Tags ＆ Cell Markers
