Background：The NF-kappa-B （NFKB） complex of proteins is inhibited by I-kappa-B （IKB） proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
仕様
Synonyms：EC 2.7.11.1,FLJ11330,FTDALS4,NAK,NF kappa B activating kinase,NF kB activating kinase,NF-kappa-B-activating kinase,Serine/threonine protein kinase TBK 1,Serine/threonine protein kinase TBK1,Serine/threonine-protein kinase TBK1,T2K,TANK binding kinase 1,TANK-binding kinase 1,TBK 1,Tbk1,TBK1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TBK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：29110
Swissprot：Q9UHD2
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
