Background：This gene encodes an inhibitor of apoptosis protein （IAP）-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：0610041G12Rik,DBLOH,DBOH,DFNA64,diablo,Diablo homolog （Drosophila）,Diablo homolog,Diablo homolog mitochondrial,Diablo IAP binding mitochondrial protein,Diablo like protein,DIABLO S,Direct IAP binding protein with low pI,Direct IAP-binding protein with low pI,FLJ10537,FLJ25049,mitochondrial,Mitochondrial Smac protein,Second mitochondria derived activator of caspase,Second mitochondria-derived activator of caspase,SMAC 3,Smac,Smac protein,SMAC3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DIABLO
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
