Background：The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
仕様
Synonyms：Cell cycle regulated protein kinase,PLK 1,PLK,PLK-1,plk1,PLK1,Polo like kinase 1,Polo-like kinase 1,Serine/threonine protein kinase 13,Serine/threonine protein kinase PLK1,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase PLK1,STPK 13,STPK13
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human PLK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：5347
Swissprot：P53350
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
