Background:The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms:1700121J11Rik,AT2C1,ATP dependent Ca(2+) pump PMR1,ATP-dependent Ca(2+) pump PMR1,ATP2C1,ATP2C1A,ATPase 2C1,ATPase Ca(2+) sequestering,ATPase Ca++ transporting type 2C member 1,AW061228,BCPM,Calcium transporting ATPase type 2C member 1,Calcium-transporting ATPase type 2C member 1,D930003G21Rik,HHD,hSPCA1,HUSSY 28,KIAA1347,MGC58010,MGC93231,OTTHUMP00000216066,OTTHUMP00000216068,OTTHUMP00000216069,OTTHUMP00000216071,OTTHUMP00000216072,OTTHUMP00000216073,OTTHUMP00000216074,OTTHUMP00000216075,PMR1,PMR1,rat,homolog of,PMR1L,Secretory pathway Ca(2+) ATPase 1,Secretory pathway Ca(2+)-transporting ATPase,Secretory pathway Ca2+/Mn2+ ATPase 1,SPCA,SPCA1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human ATP2C1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):27032
Swissprot:P98194
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction