Background：This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
仕様
Synonyms：C terminal binding protein 2,C-terminal-binding protein 2,CtBP2,CTBP2,ribeye
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human CTBP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：1488
Swissprot：P56545
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Microbiology, Neuroscience
