Background:The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
仕様
Synonyms:E3 SUMO protein ligase TRIM28,E3 SUMO-protein ligase TRIM28,FLJ29029,KAP 1,KAP-1,KRAB associated protein 1,KRAB interacting protein 1,KRAB-associated protein 1,KRAB-interacting protein 1,KRIP 1,KRIP-1,KRIP1,Nuclear corepressor KAP 1,Nuclear corepressor KAP-1,RING finger protein 96,RNF96,TF1B,TIF1 beta,TIF1-beta,TIF1B,TIF1B,Transcription intermediary factor 1 beta,Transcription intermediary factor 1-beta,Trim28,Tripartite motif containing 28,tripartite motif containing protein 28,Tripartite motif-containing protein 28
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human TRIM28
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:1000 - 1:3000 IHC1:100 - 1:200
Gene_ID(human):10155
Swissprot:Q13263
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling