Background：This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms：FLJ23071,GlcNAc transferase,HRNT1,MGC22921,O GlcNAc,O GlcNAc transferase p110 subunit,O GlcNAc transferase subunit p110,O linked N acetylglucosamine （GlcNAc） transferase （UDP N acetylglucosamine：polypeptide N acetylglucosaminyl transferase）,O linked N acetylglucosamine （GlcNAc） transferase,O linked N acetylglucosamine transferase 110 kDa subunit,O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,ogt,OGT1,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,UDP-N-acetylglucosamine：polypeptide-N-acetylglucosaminyl transferase,Uridinediphospho N acetylglucosamine：polypeptide beta N acetylglucosaminyl transferase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human OGT
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：8473
Swissprot：O15294
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
