Background：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
仕様
Synonyms：ABCC 4,ABCC4,ATP binding cassette sub family C （CFTR/MRP） member 4,ATP binding cassette sub family C member 4,ATP-binding cassette sub-family C member 4,bA464I2.1 （ATP binding cassette, sub-family C （CFTR/MRP） member 4）,bA464I2.1,Canalicular multispecific organic anion transporter ,Canalicular multispecific organic anion transporter ABC superfamily,EST170205,MOAT B,MOAT-B,MOATB,MRP 4,MRP/cMOAT related ABC transporter,MRP/cMOAT-related ABC transporter,MRP4,Multi specific organic anion transporter B,Multi-specific organic anion transporter B,Multidrug resistance associated protein 4,Multidrug resistance-associated protein 4,OTTHUMP00000018560
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ABCC4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10257
Swissprot：O15439
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
