Background:This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
仕様
Synonyms:DNA mismatch repair protein PMS1,FLJ98259,HNPCC3,hPMS1,Human homolog of yeast mutL,Mismatch repair gene PMSL1,pms1,PMS1 postmeiotic segregation increased 1 (S. cerevisiae),PMS1 postmeiotic segregation increased 1,PMS1 protein homolog 1,PMS1,PMSL1,Rhabdomyosarcoma antigen MU RMS 40.10B,Rhabdomyosarcoma antigen MU RMS 40.10E
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PMS1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.