Background:This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms:adrenomedullin binding protein,age related maculopathy susceptibility 1,AHUS 1,AHUS1,AMBP 1,AMBP1,ARMD 4,ARMD4,ARMS 1,ARMS1,beta 1 H globulin,beta 1H,beta1H,CFAH,CFH,CFHL 3,CFHL3,Complement factor H,complement factor H, isoform b,Factor H,factor H like 1,FH,FHL 1,FHL1,H factor 1 (complement),H factor 1,H factor 2 (complement),HF 1,HF 2,HF,HF1,HF2,HUS,MGC88246
Host:Rabbit
Reactivity:Human
Applications:IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human CFH
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.