Background：This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element （CRE）, an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase （HAT） that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
仕様
Synonyms：Activating transcription factor 2,Activating transcription factor 2 splice variant ATF2 var2,ATF 2,Atf-2,Atf2,ATF2 protein,ATF2,cAMP Response Element Binding Protein 2,cAMP response element binding protein CRE BP1,cAMP response element-binding protein CRE-BP1,cAMP responsive element binding protein 2,formerly,cAMP-dependent transcription factor ATF-2,cAMP-responsive element-binding protein 2,CRE BP1,CRE-BP,CREB 2,CREB-2,CREB2,CREBP1,Cyclic AMP dependent transcription factor ATF 2,Cyclic AMP-dependent transcription factor ATF-2,Cyclic AMP-responsive element-binding protein 2,D130078H02Rik,D18875,HB 16,HB16,Histone acetyltransferase ATF2,MGC105211,MGC105222,MGC111558,MGC142504,mXBP,MXBP protein,Tg（Gzma-Klra1）7Wum,TREB 7,TREB7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human ATF2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
