Background:This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:HIWI,MIWI,Piwi (Drosophila) like 1,PIWI,Piwi homolog,Piwi like 1 (drosophila),Piwi like 1,Piwi-like protein 1,PIWIL1,PIWL1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of mouse PIWIL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):57749
Swissprot:Q9JMB7
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling