Background：This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：EC 2.7.10.2,kinase Syk,KSYK,KSYK,p72-Syk,p72syk,Spleen tyrosine kinase,Syk,Tyrosine protein kinase SYK,Tyrosine-protein kinase SYK
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human SYK
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：6850
Swissprot：P43405
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Signal transduction
