Background：The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 （MAP2K5/MEK5）. It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
仕様
Synonyms：Big MAP kinase 1,BMK 1,BMK 1 kinase,BMK-1,BMK1,BMK1 Kinase,EC 2.7.11.24,ERK 4,ERK 5,ERK-5,ERK4,ERK5,Extracellular signal regulated kinase 5,Extracellular signal-regulated kinase 5,MAP kinase 7,MAPK 7,MAPK7,Mitogen activated protein kinase 7,Mitogen-activated protein kinase 7,MK07,OTTHUMP00000065906,OTTHUMP00000065907,PRKM 7,PRKM7,PROTEIN KINASE,MITOGEN-ACTIVATED,7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human MAPK7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：5598
Swissprot：Q13164
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
