Background:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms:5''-cyclic nucleotide phosphodiesterase 1B,63 kDa Cam PDE,63 kDa Cam-PDE,Calcium/calmodulin dependent 3' 5' cyclic nucleotide Phosphodiesterase 1B,Calcium/calmodulin stimulated cyclic nucleotide phosphodiesterase,Calcium/calmodulin-dependent 3'',Calmodulin stimulated phosphodiesterase PDE1B1,Cam PDE 1B,Cam PDE1B,Cam-PDE 1B,PDE 1B,PDE1B,PDE1B,PDE1B1,PDES 1B,PDES1B,Phosphodiesterase 1B,Phosphodiesterase 1B calmodulin dependent,Presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human PDE1B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.