Background：The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
仕様
Synonyms：antigen identified by monoclonal L230,CD 51,CD51,DKFZp686A08142,Integrin alpha five,integrin alpha V beta 3,Integrin alpha-5,integrin alpha-V,Integrin alpha-V light chain,integrin alphaVbeta3,integrin,alpha V （vitronectin receptor,alpha polypeptide,antigen CD51）,ITAV,ITGAV,MSK 8,Msk8,Vitronectin receptor subunit alpha,VNRA,VTNR
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human ITGAV
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3685
Swissprot：P06756
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Microbiology, Stem cells
