Background：The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha （IL1A） and interleukin 1, beta （IL1B）, and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
仕様
Synonyms：DIRA,F630041P17Rik,ICIL 1RA,ICIL-1RA,ICIL1RA,IL-1ra,IL-1ra3,IL-1RN,IL1 inhibitor,IL1F3,IL1RA,IL1RA,IL1RN （IL1F3）,IL1RN,Interleukin 1 receptor antagonist,Interleukin-1 receptor antagonist protein,Intracellular IL 1 receptor antagonist type II,Intracellular interleukin 1 receptor antagonist （icIL 1ra）,IRAP,MGC10430,MVCD4,Type II interleukin 1 receptor antagonist
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human IL1RN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
