Background：This gene is a member of the Src family of protein tyrosine kinases （PTKs）. The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：c fgr,c fgr protooncogene,c src 2 proto oncogene,c src2,Fgr,FGR,FLJ43153,Gardner Rasheed feline sarcoma viral （v fgr）,Gardner Rasheed feline sarcoma viral （v fgr） oncogene homolog,Gardner-Rasheed feline sarcoma viral （v-fgr） oncogene homolog,MGC75096,p55 c fgr protein,P55 FGR,P55-FGR,p55c fgr,p58-Fgr,p58c fgr,p58c-Fgr,Proto oncogene c Fgr,Proto oncogene tyrosine protein kinase FGR,Proto-oncogene c-Fgr,SRC 2,SRC2,Tyrosine protein kinase Fgr,Tyrosine-protein kinase Fgr
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human FGR
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
