Background：This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
仕様
Synonyms：ADH 3,ADH5,ADHX,ADHX,Alcohol dehydrogenase （class III） chi polypeptide,alcohol dehydrogenase 5 （class III） chi polypeptide,Alcohol dehydrogenase 5,Alcohol dehydrogenase class 3,Alcohol dehydrogenase class chi chain,Alcohol dehydrogenase class III,Alcohol dehydrogenase class-3,Alcohol dehydrogenase class-III,class III alcohol dehydrogenase 5 chi subunit,FALDH,FDH,formaldehyde dehydrogenase,Glutathione dependent formaldehyde dehydrogenase,Glutathione-dependent formaldehyde dehydrogenase,GSH-FDH,GSNOR,hydroxymethyllutathione dehydrogenase,S-（hydroxymethyl）glutathione dehydrogenase
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ADH5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：128
Swissprot：P11766
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
